1K2F

siah, Seven In Absentia Homolog

Summary for 1K2F

• Entry DOI: 10.2210/pdb1k2f/pdb
• Descriptor: siah-1A protein, ZINC ION, BETA-MERCAPTOETHANOL, ... (4 entities in total)
• Functional Keywords: beta-sandwich, ligase, protein binding
• Biological source: Mus musculus (house mouse)
• Cellular location: Cytoplasm: P61092
• Total number of polymer chains: 2
• Total formula weight: 43552.05

Authors

Polekhina, G.,House, C.M.,Traficante, N.,Mackay, J.P.,Relaix, F.,Sassoon, D.A.,Parker, M.W.,Bowtell, D.D.L. (deposition date: 2001-09-26, release date: 2001-12-28, Last modification date: 2011-07-13)

• Primary citation: Polekhina, G.,House, C.M.,Traficante, N.,Mackay, J.P.,Relaix, F.,Sassoon, D.A.,Parker, M.W.,Bowtell, D.D.; Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.; Nat.Struct.Biol., 9:68-75, 2002; PubMed: 11742346; DOI: 10.1038/nsb743

Experimental method

X-RAY DIFFRACTION (2.6 Å)