1K2D
Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A
1K2D の概要
エントリーDOI | 10.2210/pdb1k2d/pdb |
分子名称 | H-2 class II histocompatibility antigen, A-U alpha chain, H-2 class II histocompatibility antigen, A-U beta chain, Myelin Basic Protein peptide with 8 residue linker peptide, ... (5 entities in total) |
機能のキーワード | mhc class ii, i-au, h-2u, autoimmune disease, unique register, experimental autoimmune encephalomyelitis, myelin basic protein, immune system |
由来する生物種 | Mus musculus (house mouse) 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 46946.99 |
構造登録者 | |
主引用文献 | He, X.L.,Radu, C.,Sidney, J.,Sette, A.,Ward, E.S.,Garcia, K.C. Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au IMMUNITY, 17:83-94, 2002 Cited by PubMed: 12150894DOI: 10.1016/S1074-7613(02)00340-0 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.2 Å) |
構造検証レポート
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