1K1R

HETERODUPLEX OF CHIRALLY PURE R-METHYLPHOSPHONATE/DNA DUPLEX

Summary for 1K1R

• Entry DOI: 10.2210/pdb1k1r/pdb
• Related: 1k1h
• NMR Information: BMRB: 5245
• Descriptor: 5'-D(*TP*GP*TP*TP*TP*GP*GP*C)-3', 5'-D(*CP*(CMR)P*(RMP)P*(RMP)P*(RMP)P*(CMR)P*(RMP))-3' (2 entities in total)
• Functional Keywords: methyl phosphonate, modified dna, anti sense, aptamers, dna
• Total number of polymer chains: 2
• Total formula weight: 4512.19

Authors

Thiviyanathan, V.,Vyazovkina, K.V.,Gozansky, E.K.,Bichenkova, E.,Abramova, T.V.,Luxon, B.A.,Lebedev, A.V.,Gorenstein, D.G. (deposition date: 2001-09-25, release date: 2002-06-19, Last modification date: 2022-02-23)

• Primary citation: Thiviyanathan, V.,Vyazovkina, K.V.,Gozansky, E.K.,Bichenchova, E.,Abramova, T.V.,Luxon, B.A.,Lebedev, A.V.,Gorenstein, D.G.; Structure of hybrid backbone methylphosphonate DNA heteroduplexes: effect of R and S stereochemistry.; Biochemistry, 41:827-838, 2002; PubMed: 11790104; DOI: 10.1021/bi011551k

Experimental method

SOLUTION NMR