1K0U
Inhibition of S-adenosylhomocysteine Hydrolase by "acyclic sugar" Adenosine Analogue D-eritadenine
Replaces: 1D4GSummary for 1K0U
Entry DOI | 10.2210/pdb1k0u/pdb |
Related | 1D4G |
Descriptor | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, D-ERITADENINE, ... (4 entities in total) |
Functional Keywords | s-adenosylhomocysteine, hydrolase, d-eritadenine, inhibitor |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cytoplasm: P10760 |
Total number of polymer chains | 8 |
Total formula weight | 387058.81 |
Authors | Takusagawa, F.,Huang, Y.,Komoto, J.,Takata, Y.,Gomi, T.,Ogawa, H.,Fujioka, M.,Powell, D. (deposition date: 2001-09-20, release date: 2001-10-17, Last modification date: 2023-08-16) |
Primary citation | Huang, Y.,Komoto, J.,Takata, Y.,Powell, D.R.,Gomi, T.,Ogawa, H.,Fujioka, M.,Takusagawa, F. Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. J.Biol.Chem., 277:7477-7482, 2002 Cited by PubMed: 11741948DOI: 10.1074/jbc.M109187200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report