1JZW

Arsenate Reductase + Sodium Arsenate From E. coli

Summary for 1JZW

Entry DOI	10.2210/pdb1jzw/pdb
Related	1I9D 1J9B
Descriptor	ARSENATE REDUCTASE, SULFATE ION, SULFITE ION, ... (5 entities in total)
Functional Keywords	arsc-cys-12-thioarsenate, reaction product of arsenate reductase with arsenate, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	16876.77
Authors	Martin, P.,DeMel, S.,Shi, J.,Gladysheva, T.,Gatti, D.L.,Rosen, B.P.,Edwards, B.F. (deposition date: 2001-09-17, release date: 2001-11-28, Last modification date: 2024-10-30)
Primary citation	Martin, P.,DeMel, S.,Shi, J.,Gladysheva, T.,Gatti, D.L.,Rosen, B.P.,Edwards, B.F. Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme. Structure, 9:1071-1081, 2001 Cited by PubMed Abstract: In Escherichia coli bearing the plasmid R773, resistance to arsenite, arsenate, antimonite, and tellurite is conferred by the arsRDABC plasmid operon that codes for an ATP-dependent anion pump. The product of the arsC gene, arsenate reductase (ArsC), is required to efficiently catalyze the reduction of arsenate to arsenite prior to extrusion. PubMed: 11709171 DOI: 10.1016/S0969-2126(01)00672-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation