1JZW

Arsenate Reductase + Sodium Arsenate From E. coli

1JZW の概要

• エントリーDOI: 10.2210/pdb1jzw/pdb
• 関連するPDBエントリー: 1I9D 1J9B
• 分子名称: ARSENATE REDUCTASE, SULFATE ION, SULFITE ION, ... (5 entities in total)
• 機能のキーワード: arsc-cys-12-thioarsenate, reaction product of arsenate reductase with arsenate, oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16876.77

構造登録者

Martin, P.,DeMel, S.,Shi, J.,Gladysheva, T.,Gatti, D.L.,Rosen, B.P.,Edwards, B.F. (登録日: 2001-09-17, 公開日: 2001-11-28, 最終更新日: 2024-10-30)

主引用文献

Martin, P.,DeMel, S.,Shi, J.,Gladysheva, T.,Gatti, D.L.,Rosen, B.P.,Edwards, B.F.
Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9:1071-1081, 2001

PubMed Abstract: In Escherichia coli bearing the plasmid R773, resistance to arsenite, arsenate, antimonite, and tellurite is conferred by the arsRDABC plasmid operon that codes for an ATP-dependent anion pump. The product of the arsC gene, arsenate reductase (ArsC), is required to efficiently catalyze the reduction of arsenate to arsenite prior to extrusion.

PubMed: 11709171
DOI: 10.1016/S0969-2126(01)00672-4

実験手法

X-RAY DIFFRACTION (1.76 Å)