1JXQ
Structure of cleaved, CARD domain deleted Caspase-9
Summary for 1JXQ
Entry DOI | 10.2210/pdb1jxq/pdb |
Related | 3YGS |
Descriptor | Caspase-9, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor (3 entities in total) |
Functional Keywords | protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 126794.62 |
Authors | Renatus, M.,Stennicke, H.R.,Scott, F.L.,Liddington, R.C.,Salvesen, G.S. (deposition date: 2001-09-08, release date: 2001-12-12, Last modification date: 2023-08-16) |
Primary citation | Renatus, M.,Stennicke, H.R.,Scott, F.L.,Liddington, R.C.,Salvesen, G.S. Dimer formation drives the activation of the cell death protease caspase 9. Proc.Natl.Acad.Sci.USA, 98:14250-14255, 2001 Cited by PubMed: 11734640DOI: 10.1073/pnas.231465798 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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