1JVP

Crystal structure of human CDK2 (unphosphorylated) in complex with PKF049-365

1JVP の概要

• エントリーDOI: 10.2210/pdb1jvp/pdb
• 分子名称: Cell division protein kinase 2, 3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole (3 entities in total)
• 機能のキーワード: protein kinase, cell division, cell cycle, enzyme inhibitors, drug design, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34209.76

構造登録者

Rondeau, J.M. (登録日: 2001-08-31, 公開日: 2001-12-21, 最終更新日: 2024-02-07)

• 主引用文献: Furet, P.,Meyer, T.,Strauss, A.,Raccuglia, S.,Rondeau, J.M.; Structure-based design and protein X-ray analysis of a protein kinase inhibitor.; Bioorg.Med.Chem.Lett., 12:221-224, 2002; PubMed: 11755359; DOI: 10.1016/S0960-894X(01)00715-6

実験手法

X-RAY DIFFRACTION (1.53 Å)