1JOH

THE STRUCTURE OF ANTIAMOEBIN I, A MEMBRANE-ACTIVE PEPTIDE

1JOH の概要

• エントリーDOI: 10.2210/pdb1joh/pdb
• 関連するPDBエントリー: 1AMT 1DLZ 1EE7 1GQ0 1IH9 1M24 1OB4 1OB6 1OB7 1R9U
• 関連するBIRD辞書のPRD_ID: PRD_000161
• 分子名称: ANTIAMOEBIN I, METHANOL (2 entities in total)
• 機能のキーワード: antiamoebin i, peptaibol, antibacterial, antifungal, antibiotic
• 由来する生物種: EMERICELLOPSIS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4046.95

構造登録者

Snook, C.F.,Wallace, B.A. (登録日: 1997-10-11, 公開日: 1999-01-20, 最終更新日: 2024-12-25)

主引用文献

Snook, C.F.,Woolley, G.A.,Oliva, G.,Pattabhi, V.,Wood, S.F.,Blundell, T.L.,Wallace, B.A.
The Structure and Function of Antiamoebin I, a Proline-Rich Membrane-Active Polypeptide.
Structure, 6:783-, 1998

PubMed Abstract: Antiamoebin is a member of the peptaibol family of polypeptides and has a unique antibiotic activity: it acts as an antiamoebic agent, but does not effectively haemolyze erythrocytes even though it does exhibit membrane-modifying activity.

PubMed: 9655831
DOI: 10.1016/S0969-2126(98)00079-3

実験手法

X-RAY DIFFRACTION (1.4 Å)