Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2

Summary for 1JGN

Descriptorpolyadenylate-binding protein 1, polyadenylate-binding protein-interacting protein 2 (2 entities in total)
Functional Keywordsall-helical domain, protein-peptide complex, rna binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P11940 Q9BPZ3
Total number of polymer chains2
Total molecular weight12738.69
Kozlov, G.,Siddiqui, N.,Coillet-Matillon, S.,Ekiel, I.,Gehring, K. (deposition date: 2001-06-26, release date: 2003-06-24, Last modification date: 2011-07-13)
Primary citation
Kozlov, G.,De Crescenzo, G.,Lim, N.S.,Siddiqui, N.,Fantus, D.,Kahvejian, A.,Trempe, J.F.,Elias, D.,Ekiel, I.,Sonenberg, N.,O'Connor-McCourt, M.,Gehring, K.
Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase
EMBO J., 23:272-281, 2004
PubMed: 14685257 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600048
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers46 7.3% 40.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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PDB entries from 2020-11-25