1JG0
Crystal structure of Escherichia coli thymidylate synthase complexed with 2'-deoxyuridine-5'-monophosphate and N,O-didansyl-L-tyrosine
Summary for 1JG0
| Entry DOI | 10.2210/pdb1jg0/pdb |
| Descriptor | thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, N,O-DIDANSYL-L-TYROSINE, ... (4 entities in total) |
| Functional Keywords | thymidylate synthase, didansyl tyrosine, transferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm: P0A884 |
| Total number of polymer chains | 2 |
| Total formula weight | 62686.75 |
| Authors | Fritz, T.A.,Tondi, D.,Finer-Moore, J.S.,Costi, M.P.,Stroud, R.M. (deposition date: 2001-06-22, release date: 2002-02-08, Last modification date: 2011-07-13) |
| Primary citation | Fritz, T.A.,Tondi, D.,Finer-Moore, J.S.,Costi, M.P.,Stroud, R.M. Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase. Chem.Biol., 8:981-995, 2001 Cited by PubMed: 11590022DOI: 10.1016/S1074-5521(01)00067-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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