1JAP

COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)

Summary for 1JAP

Related PRD IDPRD_000404
DescriptorMATRIX METALLO PROTEINASE-8 (MET80 FORM), PRO-LEU-GLY-HYDROXYLAMINE, CALCIUM ION, ... (5 entities in total)
Functional Keywordsmetalloprotease, zinc-endopeptidase, metzincins, complex (metalloprotease-inhibitor) complex, complex (metalloprotease/inhibitor)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasmic granule P22894
Total number of polymer chains2
Total molecular weight18623.07
Authors
Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H. (deposition date: 1996-03-11, release date: 1996-07-11, Last modification date: 2013-02-27)
Primary citation
Bode, W.,Reinemer, P.,Huber, R.,Kleine, T.,Schnierer, S.,Tschesche, H.
The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.
EMBO J., 13:1263-1269, 1994
PubMed: 8137810 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.82 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers703.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report