1JAN

COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (PHE79 FORM)

Summary for 1JAN

• Entry DOI: 10.2210/pdb1jan/pdb
• Related PRD ID: PRD_000404
• Descriptor: MATRIX METALLO PROTEINASE-8 (PHE79 FORM), PRO-LEU-GLY-HYDROXYLAMINE INHIBITOR, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: metalloprotease, zinc-endopeptidase, metzincins, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasmic granule: P22894
• Total number of polymer chains: 2
• Total formula weight: 18770.25

Authors

Reinemer, P.,Grams, F.,Huber, R.,Kleine, T.,Schnierer, S.,Pieper, M.,Tschesche, H.,Bode, W. (deposition date: 1996-03-11, release date: 1996-07-11, Last modification date: 2012-12-12)

• Primary citation: Reinemer, P.,Grams, F.,Huber, R.,Kleine, T.,Schnierer, S.,Piper, M.,Tschesche, H.,Bode, W.; Structural implications for the role of the N terminus in the 'superactivation' of collagenases. A crystallographic study.; FEBS Lett., 338:227-233, 1994; PubMed: 8307185; DOI: 10.1016/0014-5793(94)80370-6

Experimental method

X-RAY DIFFRACTION (2.5 Å)