1J8E
Crystal structure of ligand-binding repeat CR7 from LRP
Summary for 1J8E
Entry DOI | 10.2210/pdb1j8e/pdb |
Related | 1AJJ 1CR8 1D2L |
Descriptor | LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1, CALCIUM ION (3 entities in total) |
Functional Keywords | ligand binding, calcium binding, complement-like repeat, lrp receptor, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm: Q07954 |
Total number of polymer chains | 1 |
Total formula weight | 4857.10 |
Authors | Simonovic, M.,Dolmer, K.,Huang, W.,Strickland, D.K.,Volz, K.,Gettins, P.G.W. (deposition date: 2001-05-21, release date: 2001-12-19, Last modification date: 2021-10-27) |
Primary citation | Simonovic, M.,Dolmer, K.,Huang, W.,Strickland, D.K.,Volz, K.,Gettins, P.G. Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor. Biochemistry, 40:15127-15134, 2001 Cited by PubMed: 11735395DOI: 10.1021/bi015688m PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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