1J1J

Crystal Structure of human Translin

1J1J の概要

• エントリーDOI: 10.2210/pdb1j1j/pdb
• 関連するPDBエントリー: 1KEY
• 分子名称: Translin (2 entities in total)
• 機能のキーワード: testis/brain rna binding protein, ssdna binding protein, rna binding protein, dna binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q15631
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 110501.99

構造登録者

Sugiura, I.,Sasaki, C.,Hasegawa, T.,Kohno, T.,Sugio, S.,Moriyama, H.,Kasai, M.,Matsuzaki, T. (登録日: 2002-12-06, 公開日: 2003-12-06, 最終更新日: 2023-12-27)

主引用文献

Sugiura, I.,Sasaki, C.,Hasegawa, T.,Kohno, T.,Sugio, S.,Moriyama, H.,Kasai, M.,Matsuzaki, T.
Structure of human translin at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60:674-679, 2004

PubMed Abstract: The structure of human translin at 2.2 A resolution is reported in space group C222(1). Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P2(1)2(1)2, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA.

PubMed: 15039555
DOI: 10.1107/S0907444904002549

実験手法

X-RAY DIFFRACTION (2.2 Å)