1IRI

Crystal structure of human autocrine motility factor complexed with an inhibitor

Summary for 1IRI

• Entry DOI: 10.2210/pdb1iri/pdb
• Related: 1JIQ
• Descriptor: autocrine motility factor, ERYTHOSE-4-PHOSPHATE (3 entities in total)
• Functional Keywords: cytokine, isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P06744
• Total number of polymer chains: 4
• Total formula weight: 253720.13

Authors

Tanaka, N.,Haga, A.,Uemura, H.,Akiyama, H.,Funasaka, T.,Nagase, H.,Raz, A.,Nakamura, K.T. (deposition date: 2001-10-08, release date: 2002-06-05, Last modification date: 2023-10-25)

• Primary citation: Tanaka, N.,Haga, A.,Uemura, H.,Akiyama, H.,Funasaka, T.,Nagase, H.,Raz, A.,Nakamura, K.T.; Inhibition mechanism of cytokine activity of human autocrine motility factor examined by crystal structure analyses and site-directed mutagenesis studies.; J.Mol.Biol., 318:985-997, 2002; PubMed: 12054796; DOI: 10.1016/S0022-2836(02)00186-9

Experimental method

X-RAY DIFFRACTION (2.4 Å)