1ING

INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA109 INHIBITOR

1ING の概要

• エントリーDOI: 10.2210/pdb1ing/pdb
• 分子名称: INFLUENZA A SUBTYPE N2 NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: neuraminidase, sialidase, hydrolase, o-glycosyl, hydrolase (o-glycosyl)
• 由来する生物種: Influenza A virus
• 細胞内の位置: Virion membrane (By similarity): P06820
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92175.52

構造登録者

Jedrzejas, M.J.,Luo, M. (登録日: 1995-07-07, 公開日: 1996-08-17, 最終更新日: 2020-07-29)

• 主引用文献: Singh, S.,Jedrzejas, M.J.,Air, G.M.,Luo, M.,Laver, W.G.,Brouillette, W.J.; Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction.; J.Med.Chem., 38:3217-3225, 1995; PubMed: 7650674; DOI: 10.1021/jm00017a005

実験手法

X-RAY DIFFRACTION (2.4 Å)