1IM5
Crystal Structure of Pyrazinamidase of Pyrococcus horikoshii in Complex with Zinc
Summary for 1IM5
Entry DOI | 10.2210/pdb1im5/pdb |
Related | 1ILW |
Descriptor | 180aa long hypothetical Pyrazinamidase/Nicotinamidase, ZINC ION (3 entities in total) |
Functional Keywords | pyrazinamidase, pyrazinamide, nicotinamidase, tuberculosis, pza resistance, drug resistance, metal ion catalysis, cysteine hydrolase, hydrolase, amidase, covalent catalysis |
Biological source | Pyrococcus horikoshii |
Total number of polymer chains | 1 |
Total formula weight | 20287.65 |
Authors | Du, X.,Kim, S.-H. (deposition date: 2001-05-09, release date: 2001-12-12, Last modification date: 2024-04-03) |
Primary citation | Du, X.,Wang, W.,Kim, R.,Yakota, H.,Nguyen, H.,Kim, S.H. Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii. Biochemistry, 40:14166-14172, 2001 Cited by PubMed: 11714269DOI: 10.1021/bi0115479 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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