1ILK
INTERLEUKIN-10 CRYSTAL STRUCTURE REVEALS THE FUNCTIONAL DIMER WITH AN UNEXPECTED TOPOLOGICAL SIMILARITY TO INTERFERON GAMMA
Summary for 1ILK
Entry DOI | 10.2210/pdb1ilk/pdb |
Descriptor | INTERLEUKIN-10 (2 entities in total) |
Functional Keywords | cytokine |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P22301 |
Total number of polymer chains | 1 |
Total formula weight | 17800.60 |
Authors | Zdanov, A.,Schalk-Hihi, C.,Gustchina, A.,Wlodawer, A. (deposition date: 1995-04-21, release date: 1995-07-10, Last modification date: 2024-10-16) |
Primary citation | Zdanov, A.,Schalk-Hihi, C.,Gustchina, A.,Tsang, M.,Weatherbee, J.,Wlodawer, A. Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure, 3:591-601, 1995 Cited by PubMed: 8590020DOI: 10.1016/S0969-2126(01)00193-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report