1IL0

X-RAY CRYSTAL STRUCTURE OF THE E170Q MUTANT OF HUMAN L-3-HYDROXYACYL-COA DEHYDROGENASE

Summary for 1IL0

Entry DOI	10.2210/pdb1il0/pdb
Related	1F0Y
Descriptor	3-hydroxyacyl-CoA dehydrogenase, ACETOACETYL-COENZYME A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	abortive ternary complex, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: Q16836
Total number of polymer chains	2
Total formula weight	68765.52
Authors	Barycki, J.J.,O'Brien, L.K.,Strauss, A.W.,Banaszak, L.J. (deposition date: 2001-05-07, release date: 2001-11-07, Last modification date: 2023-08-16)
Primary citation	Barycki, J.J.,O'Brien, L.K.,Strauss, A.W.,Banaszak, L.J. Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme. J.Biol.Chem., 276:36718-36726, 2001 Cited by PubMed: 11451959 DOI: 10.1074/jbc.M104839200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation