1IHI

Crystal Structure of Human Type III 3-alpha-Hydroxysteroid Dehydrogenase/Bile Acid Binding Protein (AKR1C2) Complexed with NADP+ and Ursodeoxycholate

1IHI の概要

• エントリーDOI: 10.2210/pdb1ihi/pdb
• 分子名称: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISO-URSODEOXYCHOLIC ACID (3 entities in total)
• 機能のキーワード: alpha-beta barrel, ternary complex, protein-nadp-bile acid complex, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (Potential): P52895
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75844.49

構造登録者

Jin, Y.,Stayrook, S.E.,Albert, R.H.,Palackal, N.T.,Penning, T.M.,Lewis, M. (登録日: 2001-04-19, 公開日: 2001-10-03, 最終更新日: 2023-08-16)

• 主引用文献: Jin, Y.,Stayrook, S.E.,Albert, R.H.,Palackal, N.T.,Penning, T.M.,Lewis, M.; Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.; Biochemistry, 40:10161-10168, 2001; PubMed: 11513593; DOI: 10.1021/bi010919a

実験手法

X-RAY DIFFRACTION (3 Å)