1IHH

2.4 ANGSTROM CRYSTAL STRUCTURE OF AN OXALIPLATIN 1,2-D(GPG) INTRASTRAND CROSS-LINK IN A DNA DODECAMER DUPLEX

Summary for 1IHH

Descriptor5'-D(*CP*CP*TP*CP*TP*GP*GP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3', PLATINUM (II) ION, ... (6 entities in total)
Functional Keywordsright handed dna, double helix, complexed with drug, oxaliplatin, modified, deoxynucleic acid, dna
Total number of polymer chains2
Total molecular weight7773.38
Authors
Spingler, B.,Whittington, D.A.,Lippard, S.J. (deposition date: 2001-04-19, release date: 2001-10-26, Last modification date: 2019-07-24)
Primary citation
Spingler, B.,Whittington, D.A.,Lippard, S.J.
2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex.
Inorg.Chem., 40:5596-5602, 2001
PubMed: 11599959 (PDB entries with the same primary citation)
DOI: 10.1021/ic010790t
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
?

Structure validation

ClashscoreRSRZ outliers150MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
168889
PDB entries from 2020-09-16