1IHH
2.4 ANGSTROM CRYSTAL STRUCTURE OF AN OXALIPLATIN 1,2-D(GPG) INTRASTRAND CROSS-LINK IN A DNA DODECAMER DUPLEX
Summary for 1IHH
Entry DOI | 10.2210/pdb1ihh/pdb |
Descriptor | 5'-D(*CP*CP*TP*CP*TP*GP*GP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3', PLATINUM (II) ION, ... (6 entities in total) |
Functional Keywords | right handed dna, double helix, complexed with drug, oxaliplatin, modified, deoxynucleic acid, dna |
Total number of polymer chains | 2 |
Total formula weight | 7773.38 |
Authors | Spingler, B.,Whittington, D.A.,Lippard, S.J. (deposition date: 2001-04-19, release date: 2001-10-26, Last modification date: 2024-02-07) |
Primary citation | Spingler, B.,Whittington, D.A.,Lippard, S.J. 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex. Inorg.Chem., 40:5596-5602, 2001 Cited by PubMed: 11599959DOI: 10.1021/ic010790t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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