1IBC
CRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME
Summary for 1IBC
Entry DOI | 10.2210/pdb1ibc/pdb |
Descriptor | INTERLEUKIN-1BETA CONVERTING ENZYME, PEPTIDE ACE-TRP-GLU-HIS-ASA, ... (4 entities in total) |
Functional Keywords | protease, cysteine protease, interleukin-1beta converting enzyme, ice, caspase-1, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P29466 P29466 |
Total number of polymer chains | 3 |
Total formula weight | 32293.93 |
Authors | Becker, J.W.,Rotonda, J. (deposition date: 1997-02-12, release date: 1998-02-11, Last modification date: 2024-04-03) |
Primary citation | Rano, T.A.,Timkey, T.,Peterson, E.P.,Rotonda, J.,Nicholson, D.W.,Becker, J.W.,Chapman, K.T.,Thornberry, N.A. A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE). Chem.Biol., 4:149-155, 1997 Cited by PubMed: 9190289DOI: 10.1016/S1074-5521(97)90258-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.73 Å) |
Structure validation
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