1I83
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE)
Summary for 1I83
Entry DOI | 10.2210/pdb1i83/pdb |
Related | 1D1X 1D1Y |
Descriptor | NITRIC OXIDE SYNTHASE, ACETATE ION, ZINC ION, ... (7 entities in total) |
Functional Keywords | alpha-beta fold, oxidoreductase |
Biological source | Bos taurus (cattle) |
Cellular location | Cell membrane: P29473 |
Total number of polymer chains | 2 |
Total formula weight | 102129.28 |
Authors | Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.S.,Poulos, T.L. (deposition date: 2001-03-12, release date: 2001-08-08, Last modification date: 2011-07-13) |
Primary citation | Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.,Poulos, T.L. Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276:26486-26491, 2001 Cited by PubMed: 11331290DOI: 10.1074/jbc.M102255200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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