1D1Y

BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1,3-PBITU (H4B FREE)

Summary for 1D1Y

Related1NSE 1D0C 1D0O 1D1V 1D1W 1D1X 1D1Y
DescriptorBOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN, ACETATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (9 entities in total)
Functional Keywordsalpha-beta fold, oxidoreductase
Biological sourceBos taurus (cattle)
Cellular locationCell membrane P29473
Total number of polymer chains2
Total molecular weight102196.04
Authors
Raman, C.S.,Li, H.,Martasek, P.,Southan, G.J.,Masters, B.S.S.,Poulos, T.L. (deposition date: 1999-09-21, release date: 2001-07-25, Last modification date: 2011-07-13)
Primary citation
Raman, C.S.,Li, H.,Martasek, P.,Babu, B.R.,Griffith, O.W.,Masters, B.S.,Poulos, T.L.
Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276:26486-26491, 2001
PubMed: 11331290 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M102255200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers13 0.8% 1.8% 8.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25