1I3K

MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE

Summary for 1I3K

Entry DOI	10.2210/pdb1i3k/pdb
Related	1I3L 1I3M 1I3N
Descriptor	UDP-GLUCOSE 4-EPIMERASE, CHLORIDE ION, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	galactosemia epimerase short-chain dehydrogenase, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	79581.23
Authors	Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. (deposition date: 2001-02-15, release date: 2001-06-20, Last modification date: 2023-08-09)
Primary citation	Thoden, J.B.,Wohlers, T.M.,Fridovich-Keil, J.L.,Holden, H.M. Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase. J.Biol.Chem., 276:20617-20623, 2001 Cited by PubMed: 11279193 DOI: 10.1074/jbc.M101304200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation