1HX0

Structure of pig pancreatic alpha-amylase complexed with the "truncate" acarbose molecule (pseudotrisaccharide)

1HX0 の概要

• エントリーDOI: 10.2210/pdb1hx0/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900001
• 分子名称: ALPHA AMYLASE (PPA), 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: alpha-amylase, inhibitor, carbohydrate, pancreas, hydrolase
• 由来する生物種: Sus scrofa (pig)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57690.74

構造登録者

Qian, M.,Payan, F. (登録日: 2001-01-11, 公開日: 2001-08-08, 最終更新日: 2023-10-25)

• 主引用文献: Qian, M.,Nahoum, V.,Bonicel, J.,Bischoff, H.,Henrissat, B.,Payan, F.; Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex; Biochemistry, 40:7700-7709, 2001; PubMed: 11412124; DOI: 10.1021/bi0102050

実験手法

X-RAY DIFFRACTION (1.38 Å)