1HWW

GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE

Summary for 1HWW

• Entry DOI: 10.2210/pdb1hww/pdb
• Related: 1HTY
• Descriptor: ALPHA-MANNOSIDASE II, 2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total)
• Functional Keywords: n-terminal alpha-beta domain, three helix bundle, 2 c-terminal beta barrels, hydrolase
• Biological source: Drosophila melanogaster (fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 116800.79

Authors

van den Elsen, J.M.H.,Kuntz, D.A.,Rose, D.R. (deposition date: 2001-01-10, release date: 2002-01-10, Last modification date: 2023-08-09)

• Primary citation: van den Elsen, J.M.,Kuntz, D.A.,Rose, D.R.; Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.; EMBO J., 20:3008-3017, 2001; PubMed: 11406577; DOI: 10.1093/emboj/20.12.3008

Experimental method

X-RAY DIFFRACTION (1.87 Å)