1HV5

CRYSTAL STRUCTURE OF THE STROMELYSIN-3 (MMP-11) CATALYTIC DOMAIN COMPLEXED WITH A PHOSPHINIC INHIBITOR

Summary for 1HV5

Entry DOI	10.2210/pdb1hv5/pdb
Descriptor	STROMELYSIN 3, ZINC ION, CALCIUM ION, ... (6 entities in total)
Functional Keywords	stromelysin-3, inhibition, phosphinic inhibitor, hydrolase
Biological source	Mus musculus (house mouse)
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): Q02853
Total number of polymer chains	6
Total formula weight	126976.76
Authors	Gall, A.L.,Ruff, M.,Kannan, R.,Cuniasse, P.,Yiotakis, A.,Dive, V.,Rio, M.C.,Basset, P.,Moras, D. (deposition date: 2001-01-08, release date: 2001-03-28, Last modification date: 2024-02-07)
Primary citation	Gall, A.L.,Ruff, M.,Kannan, R.,Cuniasse, P.,Yiotakis, A.,Dive, V.,Rio, M.C.,Basset, P.,Moras, D. Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state. J.Mol.Biol., 307:577-586, 2001 Cited by PubMed: 11254383 DOI: 10.1006/jmbi.2001.4493 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation