1HUU

DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS

Summary for 1HUU

Entry DOI	10.2210/pdb1huu/pdb
Descriptor	PROTEIN HU (2 entities in total)
Functional Keywords	dna-binding protein, dna supercoiling, alpha/beta class, minor groove binder, dna binding protein
Biological source	Geobacillus stearothermophilus
Total number of polymer chains	3
Total formula weight	29199.50
Authors	White, S.W.,Tanaka, I.,Appelt, K.,Wilson, K.S. (deposition date: 1998-07-06, release date: 1999-01-13, Last modification date: 2024-02-07)
Primary citation	White, S.W.,Appelt, K.,Wilson, K.S.,Tanaka, I. A protein structural motif that bends DNA. Proteins, 5:281-288, 1989 Cited by PubMed Abstract: The prokaryotic protein HU, integration host factor (IHF) from Escherichia coli, and transcription factor 1 (TF1) from bacteriophage SPO1 are closely related molecules. Biochemical results suggest that the role of these proteins is to bind and bend DNA. From the high-resolution structure of HU, we propose a model for this interaction with DNA. Crucial amino acid differences between the proteins can be rationalized in terms of their different specific functions. PubMed: 2508086 DOI: 10.1002/prot.340050405 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation