1HP0

CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE

Summary for 1HP0

Entry DOI	10.2210/pdb1hp0/pdb
Related	1EZR 1HOZ 1MAS 2MAS
Descriptor	INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, 3-DEAZA-ADENOSINE, ... (4 entities in total)
Functional Keywords	rossmann-fold-like motif, hydrolase
Biological source	Trypanosoma vivax
Total number of polymer chains	2
Total formula weight	76050.63
Authors	Versees, W.,Decanniere, K.,Pelle, R.,Depoorter, J.,Parkin, D.W.,Steyaert, J. (deposition date: 2000-12-12, release date: 2001-12-12, Last modification date: 2023-08-09)
Primary citation	Versees, W.,Decanniere, K.,Pelle, R.,Depoorter, J.,Brosens, E.,Parkin, D.W.,Steyaert, J. Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax. J.Mol.Biol., 307:1363-1379, 2001 Cited by PubMed: 11292348 DOI: 10.1006/jmbi.2001.4548 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation