1HP0
CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE | polymer | 339 | 37719.0 | 2 | UniProt (Q9GPQ4) | Trypanosoma vivax | IAG-NUCLEOSIDE HYDROLASE, IAG-NH |
| 2 | C, E (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 3 | D, F (A, B) | 3-DEAZA-ADENOSINE | non-polymer | 266.3 | 2 | Chemie (AD3) PubChem (1651) PubChem (176735355) PubChem (177678932) PubChem (29976739) PubChem (29976742) PubChem (23190) PubChem (44386188) PubChem (45038778) PubChem (46873944) PubChem (46937005) PubChem (44367024) PubChem (59036309) PubChem (688459) PubChem (92852183) PubChem (93055319) PubChem (94199777) PubChem (124423261) PubChem (12769724) PubChem (12769725) PubChem (134692539) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 327 (UniProt: Q9GPQ4)
| PDB | External Database | Details |
|---|---|---|
| Met -12 | - | expression tag |
| Arg -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Pro -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 301 | Lys 301 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75438.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 612.7 | |
| All* | Total formula weight | 76050.6 |
