1HP0

CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE	polymer	339	37719.0	2	UniProt (Q9GPQ4) Pfam (PF01156)	Trypanosoma vivax	IAG-NUCLEOSIDE HYDROLASE, IAG-NH
2	C, E (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, F (A, B)	3-DEAZA-ADENOSINE	non-polymer		266.3	2	Chemie (AD3)
4	G, H (A, B)	water	water		18.0	395	Chemie (HOH)

Sequence modifications

A, B: 2 - 327 (UniProt: Q9GPQ4)

PDB	External Database	Details
Met -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Pro -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 301	Lys 301	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75438.0
Non-Polymers*	Number of molecules	4
	Total formula weight	612.7
All*	Total formula weight	76050.6

*Water molecules are not included.