1HM9

CRYSTAL STRUCTURE OF S.PNEUMONIAE N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, GLMU, BOUND TO ACETYL COENZYME A AND UDP-N-ACETYLGLUCOSAMINE

Summary for 1HM9

Entry DOI	10.2210/pdb1hm9/pdb
Related	1FWY 1FXJ 1HM0 1HM8
Descriptor	UDP-N-ACETYLGLUCOSAMINE-1-PHOSPHATE URIDYLTRANSFERASE, CALCIUM ION, ACETYL COENZYME *A, ... (5 entities in total)
Functional Keywords	acetyltransferase, bifunctional, drug design, pyrophosphorylase, rossmann-like fold, left-handed-beta-helix, trimer, domain-interchange, transferase
Biological source	Streptococcus pneumoniae
Total number of polymer chains	2
Total formula weight	104233.68
Authors	Sulzenbacher, G.,Gal, L.,Peneff, C.,Fassy, F.,Bourne, Y. (deposition date: 2000-12-05, release date: 2001-11-30, Last modification date: 2023-08-09)
Primary citation	Sulzenbacher, G.,Gal, L.,Peneff, C.,Fassy, F.,Bourne, Y. Crystal structure of Streptococcus pneumoniae N-acetylglucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture. J.Biol.Chem., 276:11844-11851, 2001 Cited by PubMed: 11118459 DOI: 10.1074/jbc.M011225200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation