1HKK

High resoultion crystal structure of human chitinase in complex with allosamidin

Summary for 1HKK

Entry DOI	10.2210/pdb1hkk/pdb
Related	1GUV 1HKI 1HKJ 1HKM 1LG1 1LG2 1LQ0 1WAW 1WB0
Descriptor	CHITOTRIOSIDASE-1, 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, ... (5 entities in total)
Functional Keywords	human chitinase, hydrolase, chitin degradation, allosamidin
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	42174.13
Authors	Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Sakuda, S.,Van Aalten, D.M.F. (deposition date: 2003-03-10, release date: 2004-03-11, Last modification date: 2023-12-13)
Primary citation	Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Sakuda, S.,Van Aalten, D.M.F. Crystal Structures of Allosamidin Derivatives in Complex with Human Macrophage Chitinase. J.Biol.Chem., 278:20110-, 2003 Cited by PubMed: 12639956 DOI: 10.1074/JBC.M300362200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation