1HK5
HUMAN SERUM ALBUMIN MUTANT R218H COMPLEXED WITH THYROXINE (3,3',5,5'-TETRAIODO-L-THYRONINE) and myristic acid (tetradecanoic acid)
Summary for 1HK5
Entry DOI | 10.2210/pdb1hk5/pdb |
Related | 1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1O9X 1UOR |
Descriptor | SERUM ALBUMIN, MYRISTIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... (4 entities in total) |
Functional Keywords | plasma protein, hormone-binding, lipid-binding, thyroxine, familial dysalbuminemic hyperthyroxinemia |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 1 |
Total formula weight | 68927.64 |
Authors | Petitpas, I.,Petersen, C.E.,Ha, C.E.,Bhattacharya, A.A.,Zunszain, P.A.,Ghuman, J.,Bhagavan, N.V.,Curry, S. (deposition date: 2003-03-05, release date: 2003-05-16, Last modification date: 2023-12-13) |
Primary citation | Petitpas, I.,Petersen, C.E.,Ha, C.E.,Bhattacharya, A.A.,Zunszain, P.A.,Ghuman, J.,Bhagavan, N.V.,Curry, S. Structural Basis of Albumin-Thyroxine Interactions and Familial Dysalbuminemic Hyperthyroxinemia Proc.Natl.Acad.Sci.USA, 100:6440-, 2003 Cited by PubMed: 12743361DOI: 10.1073/PNAS.1137188100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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