1HEZ

Structure of P. magnus protein L bound to a human IgM Fab.

1HEZ の概要

• エントリーDOI: 10.2210/pdb1hez/pdb
• 分子名称: KAPPA LIGHT CHAIN OF IG, HEAVY CHAIN OF IG, PROTEIN L, ... (5 entities in total)
• 機能のキーワード: antibody, superantigen
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 102220.67

構造登録者

Graille, M.,Stura, E.A.,Housden, N.G.,Bottomley, S.P.,Taussig, M.J.,Sutton, B.J.,Gore, M.G.,Charbonnier, J.B. (登録日: 2000-11-27, 公開日: 2001-08-10, 最終更新日: 2024-11-20)

主引用文献

Graille, M.,Stura, E.A.,Housden, N.G.,Beckingham, J.A.,Bottomley, S.P.,Beale, D.,Taussig, M.J.,Sutton, B.J.,Gore, M.G.,Charbonnier, J.B.
Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9:679-, 2001

PubMed Abstract: Peptostreptococcus magnus protein L (PpL) is a multidomain, bacterial surface protein whose presence correlates with virulence. It consists of up to five homologous immunoglobulin binding domains that interact with the variable (VL) regions of kappa light chains found on two thirds of mammalian antibodies.

PubMed: 11587642
DOI: 10.1016/S0969-2126(01)00630-X

実験手法

X-RAY DIFFRACTION (2.7 Å)