1HDC

MECHANISM OF INHIBITION OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE BY A LICORICE-DERIVED STEROIDAL INHIBITOR

Summary for 1HDC

Entry DOI	10.2210/pdb1hdc/pdb
Descriptor	3-ALPHA, 20 BETA-HYDROXYSTEROID DEHYDROGENASE, CARBENOXOLONE (3 entities in total)
Functional Keywords	oxidoreductase
Biological source	Streptomyces exfoliatus
Total number of polymer chains	4
Total formula weight	107845.81
Authors	Ghosh, D. (deposition date: 1994-10-21, release date: 1995-02-07, Last modification date: 2024-02-07)
Primary citation	Ghosh, D.,Erman, M.,Wawrzak, Z.,Duax, W.L.,Pangborn, W. Mechanism of inhibition of 3 alpha, 20 beta-hydroxysteroid dehydrogenase by a licorice-derived steroidal inhibitor. Structure, 2:973-980, 1994 Cited by PubMed: 7866748 DOI: 10.1016/S0969-2126(94)00099-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation