1HAK

CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLACENTAL ANNEXIN V COMPLEXED WITH K-201 AS A CALCIUM CHANNEL ACTIVITY INHIBITOR

1HAK の概要

• エントリーDOI: 10.2210/pdb1hak/pdb
• 分子名称: ANNEXIN V, 4-[3-{1-(4-BENZYL)PIPERODINYL}PROPIONYL]-7-METHOXY-2,3,4,5-TERTRAHYDRO-1,4-BENZOTHIAZEPINE (3 entities in total)
• 機能のキーワード: annexin v, lipocortin v, endonexin ii, placenta anticoagulant protein-i, 35kda calelectrin, inhibitor of blood coagulation, calcium/phospholipid-binding, calcium-phospholipid-binding complex
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72810.61

構造登録者

Ago, H.,Inagaki, E.,Miyano, M. (登録日: 1997-12-10, 公開日: 1999-02-16, 最終更新日: 2023-08-09)

• 主引用文献: Kaneko, N.,Ago, H.,Matsuda, R.,Inagaki, E.,Miyano, M.; Crystal structure of annexin V with its ligand K-201 as a calcium channel activity inhibitor.; J.Mol.Biol., 274:16-20, 1997; PubMed: 9398511; DOI: 10.1006/jmbi.1997.1375

実験手法

X-RAY DIFFRACTION (3 Å)