1H6E

MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH CTLA-4 INTERNALIZATION PEPTIDE TTGVYVKMPPT

Summary for 1H6E

Entry DOI	10.2210/pdb1h6e/pdb
Related	1BW8 1BXX 1HES 1I31
Descriptor	CLATHRIN COAT ASSEMBLY PROTEIN AP50, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 (2 entities in total)
Functional Keywords	endocytosis/exocytosis, endocytosis, adaptor, peptide complex, phosphorylation, endocytosis-exocytosis complex
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	34208.94
Authors	Rowsell, S.,Pauptit, R.A. (deposition date: 2001-06-12, release date: 2001-11-28, Last modification date: 2023-12-13)
Primary citation	Follows, E.R.,Mcpheat, J.C.,Minshull, C.,Moore, N.C.,Pauptit, R.A.,Rowsell, S.,Stacey, C.L.,Stanway, J.J.,Taylor, I.W.,Abbott, W.M. Study of the Interaction of the Medium Chain Mu2 Subunit of the Clathrin-Associated Adapter Protein Complex 2 with Cytotoxic T-Lymphocyte Antigen 4 and Cd28 Biochem.J., 359:427-, 2001 Cited by PubMed: 11583591 DOI: 10.1042/0264-6021:3590427 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation