1H2Y

PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, Y473F MUTANT WITH COVALENTLY BOUND INHIBITOR Z-PRO-PROLINAL

Summary for 1H2Y

Entry DOI	10.2210/pdb1h2y/pdb
Related	1E5T 1E8M 1E8N 1H2W 1H2X 1H2Z 1O6F 1O6G 1QFM 1QFS
Related PRD ID	PRD_000692
Descriptor	PROLYL ENDOPEPTIDASE, N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, GLYCEROL, ... (4 entities in total)
Functional Keywords	hydrolase, prolyl oligopeptidase, amnesia, alpha/ beta- hydrolase, beta-propeller, serine protease
Biological source	SUS SCROFA (PIG)
Cellular location	Cytoplasm: P23687
Total number of polymer chains	1
Total formula weight	81639.19
Authors	Rea, D.,Fulop, V. (deposition date: 2002-08-20, release date: 2002-11-11, Last modification date: 2023-12-13)
Primary citation	Szeltner, Z.,Rea, D.,Renner, V.,Fulop, V.,Polgar, L. Electrostatic Effects and Binding Determinants in the Catalysis of Prolyl Oligopeptidase: Site Specific Mutagenesis at the Oxyanion Binding Site J.Biol.Chem., 277:42613-, 2002 Cited by PubMed: 12202494 DOI: 10.1074/JBC.M208043200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation