1GW6
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT
Summary for 1GW6
Entry DOI | 10.2210/pdb1gw6/pdb |
Related | 1HS6 |
Descriptor | LEUKOTRIENE A-4 HYDROLASE, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ACETATE ION, ... (7 entities in total) |
Functional Keywords | hydrolase, mutagenesis studies, alpha-beta protein |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: P09960 |
Total number of polymer chains | 1 |
Total formula weight | 69906.74 |
Authors | Rudberg, P.C.,Tholander, F.,Thunnissen, M.M.G.M.,Samuelsson, B.,Haeggstrom, J.Z. (deposition date: 2002-03-07, release date: 2003-03-06, Last modification date: 2023-12-13) |
Primary citation | Rudberg, P.C.,Tholander, F.,Thunnissen, M.M.G.M.,Samuelsson, B.,Haeggstrom, J.Z. Leukotriene A4 Hydrolase: Selective Abrogation of Leukotriene B4 Formation by Mutation of Aspartic Acid 375 Proc.Natl.Acad.Sci.USA, 99:4215-, 2002 Cited by PubMed: 11917124DOI: 10.1073/PNAS.072090099 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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