1GP9

A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping

1GP9 の概要

• エントリーDOI: 10.2210/pdb1gp9/pdb
• 関連するPDBエントリー: 1BHT 1GMN 1GMO 1NK1 2HGF
• 分子名称: HEPATOCYTE GROWTH FACTOR, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
• 機能のキーワード: hormone/growth factor, hgf/sf, nk1, met, domain swapping, protein engineering, growth factor, kringle, glycoprotein, hormone-growth factor complex
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 82508.44

構造登録者

Watanabe, K.,Chirgadze, D.Y.,Lietha, D.,Gherardi, E.,Blundell, T.L. (登録日: 2001-10-31, 公開日: 2001-11-19, 最終更新日: 2023-12-13)

• 主引用文献: Watanabe, K.,Chirgadze, D.Y.,Lietha, D.,De Jonge, H.,Blundell, T.L.,Gherardi, E.; A New Crystal Form of the Nk1 Splice Variant of Hgf/Sf Demonstrates Extensive Hinge Movement and Suggests that the Nk1 Dimer Originates by Domain Swapping; J.Mol.Biol., 319:283-, 2002; PubMed: 12051906; DOI: 10.1016/S0022-2836(02)00199-7

実験手法

X-RAY DIFFRACTION (2.5 Å)