1GKD
MMP9 active site mutant-inhibitor complex
Summary for 1GKD
Entry DOI | 10.2210/pdb1gkd/pdb |
Descriptor | 92 KDA TYPE IV COLLAGENASE, CALCIUM ION, 2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID, ... (6 entities in total) |
Functional Keywords | matrix metalloprotease, hydrolase, glycoprotein |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P14780 |
Total number of polymer chains | 2 |
Total formula weight | 38015.96 |
Authors | Rowsell, S.,Pauptit, R.A. (deposition date: 2001-08-10, release date: 2002-05-16, Last modification date: 2023-12-13) |
Primary citation | Rowsell, S.,Hawtin, P.,Minshull, C.A.,Jepson, H.,Brockbank, S.,Barratt, D.,Slater, A.M.,Mcpheat, W.,Waterson, D.,Henney, A.,Pauptit, R.A. Crystal Structure of Mmp9 in Complex with a Reverse Hydroxamate Inhibitor J.Mol.Biol., 319:173-, 2002 Cited by PubMed: 12051944DOI: 10.1016/S0022-2836(02)00262-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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