1GH7

CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA-COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF

1GH7 の概要

• エントリーDOI: 10.2210/pdb1gh7/pdb
• 分子名称: CYTOKINE RECEPTOR COMMON BETA CHAIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: dimer of interlocking chains of fibronectin-iii domains four fibronectin-iii domains per chain, cytokine receptor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 97939.11

構造登録者

Carr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G. (登録日: 2000-11-27, 公開日: 2001-11-28, 最終更新日: 2023-12-27)

• 主引用文献: Carr, P.D.,Gustin, S.E.,Church, A.P.,Murphy, J.M.,Ford, S.C.,Mann, D.A.,Woltring, D.M.,Walker, I.,Ollis, D.L.,Young, I.G.; Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.; Cell(Cambridge,Mass.), 104:291-300, 2001; PubMed: 11207369; DOI: 10.1016/S0092-8674(01)00213-6

実験手法

X-RAY DIFFRACTION (3 Å)