1G8M

CRYSTAL STRUCTURE OF AVIAN ATIC, A BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME IN PURINE BIOSYNTHESIS AT 1.75 ANG. RESOLUTION

1G8M の概要

• エントリーDOI: 10.2210/pdb1g8m/pdb
• 分子名称: AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, POTASSIUM ION, GUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: homodimer, 2 functional domains; impch domain = alpha/beta/alpha; aicar tfase = 2 alpha/beta/alpha domains, 1 alpha + beta domain, transferase, hydrolase
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 130374.73

構造登録者

Greasley, S.E.,Horton, P.,Beardsley, G.P.,Benkovic, S.J.,Wilson, I.A. (登録日: 2000-11-17, 公開日: 2001-04-27, 最終更新日: 2017-10-04)

• 主引用文献: Greasley, S.E.,Horton, P.,Ramcharan, J.,Beardsley, G.P.,Benkovic, S.J.,Wilson, I.A.; Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.; Nat.Struct.Biol., 8:402-406, 2001; PubMed: 11323713; DOI: 10.1038/87555

実験手法

X-RAY DIFFRACTION (1.75 Å)