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1G5Y

THE 2.0 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN TETRAMER IN THE PRESENCE OF A NON-ACTIVATING RETINOIC ACID ISOMER.

Summary for 1G5Y
Entry DOI10.2210/pdb1g5y/pdb
Related1FM6 1FM9 1G1U 1LBD
DescriptorRETINOIC ACID RECEPTOR RXR-ALPHA, RETINOIC ACID (3 entities in total)
Functional Keywordsrxralpha ligand binding domain, inactive tetramer with 2 monomers bound with an inactivating isomer of retinoic acid, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus : P19793
Total number of polymer chains4
Total formula weight107272.30
Authors
Gampe Jr., R.T.,Montana, V.G.,Lambert, M.H.,Wisely, G.B.,Milburn, M.V.,Xu, H.E. (deposition date: 2000-11-02, release date: 2001-05-02, Last modification date: 2018-04-25)
Primary citationGampe Jr., R.T.,Montana, V.G.,Lambert, M.H.,Wisely, G.B.,Milburn, M.V.,Xu, H.E.
Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix.
Genes Dev., 14:2229-2241, 2000
Cited by
PubMed: 10970886
DOI: 10.1101/gad.802300
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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