1G52

CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2,3-DIFLUOROPHENYL)METHYL]-BENZAMIDE

Summary for 1G52

Entry DOI	10.2210/pdb1g52/pdb
Related	1g1d 1g3z 1g45 1g46 1g48 1g4j 1g4o
Descriptor	CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	carbonic anhydrase ii, 4-(aminosulfonyl)-n-[(2, 3-difluorophenyl)methyl]-benzamide, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29750.18
Authors	Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. (deposition date: 2000-10-30, release date: 2000-11-08, Last modification date: 2024-02-07)
Primary citation	Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. Contribution of Fluorine to Protein-Ligand Affinity in the Binding of Fluoroaromatic Inhibitors to Carbonic Anhydrase II J.Am.Chem.Soc., 122:12125-12134, 2000 Cited by DOI: 10.1021/ja002627n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation