1G1D

CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2-FLUOROPHENYL)METHYL]-BENZAMIDE

Summary for 1G1D

• Entry DOI: 10.2210/pdb1g1d/pdb
• Descriptor: CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
• Functional Keywords: carbonic anhydrase ii, 4-(aminosulfonyl)-n-[(2-fluorophenyl)methyl]-benzamide, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29732.19

Authors

Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. (deposition date: 2000-10-11, release date: 2000-11-08, Last modification date: 2024-02-07)

• Primary citation: Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W.; Contribution of Fluorine to Protein-Ligand Affinity in the Binding of Fluoroaromatic Inhibitors to Carbonic Anhydrase II; J.Am.Chem.Soc., 122:12125-12134, 2000; DOI: 10.1021/ja002627n

Experimental method

X-RAY DIFFRACTION (2.04 Å)