1G1D
CARBONIC ANHYDRASE II COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2-FLUOROPHENYL)METHYL]-BENZAMIDE
Summary for 1G1D
Entry DOI | 10.2210/pdb1g1d/pdb |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase ii, 4-(aminosulfonyl)-n-[(2-fluorophenyl)methyl]-benzamide, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29732.19 |
Authors | Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. (deposition date: 2000-10-11, release date: 2000-11-08, Last modification date: 2024-02-07) |
Primary citation | Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. Contribution of Fluorine to Protein-Ligand Affinity in the Binding of Fluoroaromatic Inhibitors to Carbonic Anhydrase II J.Am.Chem.Soc., 122:12125-12134, 2000 Cited by DOI: 10.1021/ja002627nPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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