1G1F

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH A TRI-PHOSPHORYLATED PEPTIDE (RDI(PTR)ETD(PTR)(PTR)RK) FROM THE INSULIN RECEPTOR KINASE

1G1F の概要

• エントリーDOI: 10.2210/pdb1g1f/pdb
• 分子名称: PROTEIN TYROSINE PHOSPHATASE 1B, TRI-PHOSPHORYLATED PEPTIDE FROM THE INSULIN RECEPTOR KINASE (3 entities in total)
• 機能のキーワード: hydrolase (phosphorylation), tyrosine phosphatase, peptide complex, hydrolase, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36453.10

構造登録者

Salmeen, A.,Andersen, J.N.,Myers, M.P.,Tonks, N.K.,Barford, D. (登録日: 2000-10-11, 公開日: 2001-01-17, 最終更新日: 2021-11-03)

• 主引用文献: Salmeen, A.,Andersen, J.N.,Myers, M.P.,Tonks, N.K.,Barford, D.; Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.; Mol.Cell, 6:1401-1412, 2000; PubMed: 11163213; DOI: 10.1016/S1097-2765(00)00137-4

実験手法

X-RAY DIFFRACTION (2 Å)