1G0W

CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE

1G0W の概要

• エントリーDOI: 10.2210/pdb1g0w/pdb
• 分子名称: CREATINE KINASE, SULFATE ION (3 entities in total)
• 機能のキーワード: brain-type creatine kinase, guanidino kinase cellular energy metabolism, transferase
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Cytoplasm (By similarity): Q9XSC6
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42826.22

構造登録者

Tisi, D.,Bax, B.,Loew, A. (登録日: 2000-10-09, 公開日: 2001-02-07, 最終更新日: 2024-02-07)

主引用文献

Tisi, D.,Bax, B.,Loew, A.
The three-dimensional structure of cytosolic bovine retinal creatine kinase.
Acta Crystallogr.,Sect.D, 57:187-193, 2001

PubMed Abstract: Creatine kinase (CK) catalyses the reversible transfer of the phosphate moiety from phosphocreatine (PCr) to ADP, generating creatine and ATP. The crystal structure of a cytosolic brain-type creatine kinase is reported at 2.3 A. The biological dimer sits on a crystallographic twofold axis. The N-terminal residues of both subunits come very close to the crystallographic twofold at the dimer interface. The electron density observed is consistent with two alternative conformations for the N-termini, as previously found for chicken brain-type creatine kinase.

PubMed: 11173463
DOI: 10.1107/S0907444900015614

実験手法

X-RAY DIFFRACTION (2.3 Å)